Salary data · South Carolina
physician assistant salary in South Carolina
physician assistants in South Carolina earn a mean of $120,720 a year and a median of $122,490. That ranks 45th of the 51 states with a published estimate.
$120,720
Mean annual wage
about $58 an hour
$122,490
Median annual wage
45th of 51
State rank
by mean wage
2,250
PAs employed
BLS estimate
Source: BLS OEWS, May 2025 estimates. These are estimates for physician assistants already employed in South Carolina, not offers; the hourly figure divides the annual mean by 2,080 hours. Setting, specialty and caseload move an individual offer well above or below them. Updated October 22, 2026.
Open roles
PA openings in South Carolina
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